Assay Detail
Binding
CHEMBL707235
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Compound tested for binding affinity against Leukotriene B4 receptor using radioligand binding assay from Human PMN cells
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Cell Type | PMN |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
A novel series of [2-[methyl(2-phenethyl)amino]-2-oxoethyl] benzene-containing leukotriene B4 antagonists: initial structure-activity relationships.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.23 | 8.33 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL328712 | — | — | 1 | 8.33 |
| CHEMBL124717 | — | — | 1 | 7.30 |
| CHEMBL121748 | — | — | 1 | 6.05 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL328712 | — | IC50 | = | 4.7 | nM | 8.33 |
| CHEMBL124717 | — | IC50 | = | 50.0 | nM | 7.30 |
| CHEMBL121748 | — | IC50 | = | 900.0 | nM | 6.05 |