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Assay Detail

CHEMBL707242

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Compound was evaluated in a human neutrophil leukotriene B4 receptor binding assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Leukotriene B4 receptor 1 (CHEMBL3911)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

7-[3-(4-acetyl-3-methoxy-2-propylphenoxy)propoxy]-3,4-dihydro-8- propyl-2H-1-benzopyran-2-carboxylic acid: an orally active selective leukotriene B4 receptor antagonist.
Djuric SW, Collins PW, Jones PH, Shone RL, Tsai BS, Fretland DJ, Butchko GM, Villani-Price D, Keith RH, Zemaitis JM.
J Med Chem (1989) 32 : 1145 -1147
PubMed 2542550 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.52 6.52

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL14823 SC-41390 1 6.52

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL14823 SC-41390 IC50 = 300.0 nM 6.52