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Assay Detail

CHEMBL707812

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Compound was tested for inhibitory activity against HIV in whole cell assay (MT-4, RF strain of HIV-1 at a concentration up to 425 uM)
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type MT4
Confidence 1 — Organism
Curated By Intermediate

Target

MT4 (CHEMBL388)
Type CELL-LINE
Organism Homo sapiens

Publication

Antiviral optically pure dioxolane purine nucleosides analogues
Siddiqui M, Brown WL, Nguyen-Ba N, Dixit DM, Mansour TS, Hooker E, Viner K, Cameron JM
Bioorg Med Chem Lett (1993) 3 : 1543 -1546
· DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 5.43 5.89

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL38860 1 5.89
CHEMBL417332 1 4.97

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL38860 IC50 = 1300.0 nM 5.89
CHEMBL417332 IC50 = 10700.0 nM 4.97