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Assay Detail

CHEMBL708398

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Affinity for guinea pig PMN LTB-4 receptors.
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Cavia porcellus
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Leukotriene B4 receptor 1 (CHEMBL3911)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

4-[2-[Methyl(2-phenethyl)amino]-2-oxoethyl]-8-(phenylmethoxy)-2- naphthalenecarboxylic acid: a high affinity, competitive, orally active leukotriene B4 receptor antagonist.
Huang FC, Chan WK, Warus JD, Morrissette MM, Moriarty KJ, Chang MN, Travis JJ, Mitchell LS, Nuss GW, Sutherland CA.
J Med Chem (1992) 35 : 4253 -4255
PubMed 1331462 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 9.85 9.85

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL328712 1 9.85

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL328712 Ki = 0.14 nM 9.85