Assay Detail
Functional
CHEMBL708563
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Inhibitory concentration to reduce the growth of L1210 cells by 50% after 70 hr.
11
Total Activities
11
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | L1210 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Redox chemistry of the 9-anilinoacridine class of antitumor agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 11 | 7.12 | 8.46 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL48931 | — | — | 1 | 8.46 |
| CHEMBL9807 | — | — | 1 | 7.82 |
| CHEMBL50825 | — | — | 1 | 7.70 |
| CHEMBL9806 | — | — | 1 | 7.46 |
| CHEMBL278384 | — | — | 1 | 7.22 |
| CHEMBL22062 | — | — | 1 | 7.00 |
| CHEMBL415467 | — | — | 1 | 6.75 |
| CHEMBL48490 | — | — | 1 | 6.60 |
| CHEMBL49609 | — | — | 1 | 6.60 |
| CHEMBL289352 | — | — | 1 | 6.46 |
| CHEMBL34941 | — | — | 1 | 6.22 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL48931 | — | IC50 | = | 3.5 | nM | 8.46 |
| CHEMBL9807 | — | IC50 | = | 15.0 | nM | 7.82 |
| CHEMBL50825 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL9806 | — | IC50 | = | 35.0 | nM | 7.46 |
| CHEMBL278384 | — | IC50 | = | 60.0 | nM | 7.22 |
| CHEMBL22062 | — | IC50 | = | 100.0 | nM | 7.00 |
| CHEMBL415467 | — | IC50 | = | 180.0 | nM | 6.75 |
| CHEMBL48490 | — | IC50 | = | 250.0 | nM | 6.60 |
| CHEMBL49609 | — | IC50 | = | 250.0 | nM | 6.60 |
| CHEMBL289352 | — | IC50 | = | 350.0 | nM | 6.46 |
| CHEMBL34941 | — | IC50 | = | 600.0 | nM | 6.22 |