Assay Detail
Functional
CHEMBL708981
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In vitro cytotoxicity activity against M4 Dau, by colony forming assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Synthesis and in vitro evaluation of quaternary ammonium derivatives of chlorambucil and melphalan, anticancer drugs designed for the chemotherapy of chondrosarcoma.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.65 | 5.82 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL515 | CHLORAMBUCIL | 4.0 | 1 | 5.82 |
| CHEMBL538105 | — | — | 1 | 5.48 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL515 | CHLORAMBUCIL | IC50 | = | 1500.0 | nM | 5.82 |
| CHEMBL538105 | — | IC50 | = | 3300.0 | nM | 5.48 |