Assay Detail
Binding
CHEMBL709893
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of matrix metalloprotease-1
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Expert |
Publication
Novel inhibitors of procollagen C-proteinase. Part 2: glutamic acid hydroxamates.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 6 | 5.73 | 7.05 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL80486 | — | — | 1 | 7.05 |
| CHEMBL432532 | — | — | 1 | 6.92 |
| CHEMBL262758 | — | — | 1 | 4.50 |
| CHEMBL449092 | — | — | 1 | 4.43 |
| CHEMBL311367 | — | — | 1 | - |
| CHEMBL307057 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL80486 | — | Ki | = | 90.0 | nM | 7.05 |
| CHEMBL432532 | — | Ki | = | 120.0 | nM | 6.92 |
| CHEMBL262758 | — | Ki | = | 32000.0 | nM | 4.50 |
| CHEMBL449092 | — | Ki | = | 37000.0 | nM | 4.43 |
| CHEMBL311367 | — | Ki | > | 40000.0 | nM | - |
| CHEMBL307057 | — | Ki | > | 40000.0 | nM | - |