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Assay Detail

CHEMBL710019

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Effective concentration was measured against frog skin(MCR) cells at 10 e-4 10 e-12 M Concentration.
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism frog
Cell Type MCR
Confidence 1 — Organism
Curated By Intermediate

Target

MCR (CHEMBL614332)
Type CELL-LINE
Organism Anura

Publication

Discovery of prototype peptidomimetic agonists at the human melanocortin receptors MC1R and MC4R.
Haskell-Luevano C, Hendrata S, North C, Sawyer TK, Hadley ME, Hruby VJ, Dickinson C, Gantz I.
J Med Chem (1997) 40 : 2133 -2139
PubMed 9216831 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 2 5.17 5.82

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL65339 1 5.82
CHEMBL432895 1 4.52

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL65339 EC50 = 1500.0 nM 5.82
CHEMBL432895 EC50 = 30000.0 nM 4.52