Assay Detail
Functional
CHEMBL710086
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Effective concentration required to inhibit cytopathicity of HIV-2(ROD) in MT-4 cells
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MT4 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Design, synthesis, anti-HIV activities, and metabolic stabilities of alkenyldiarylmethane (ADAM) non-nucleoside reverse transcriptase inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 4 | 4.57 | 4.60 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL294840 | — | — | 1 | 4.60 |
| CHEMBL110224 | — | — | 1 | 4.58 |
| CHEMBL110175 | — | — | 1 | 4.53 |
| CHEMBL106554 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL294840 | — | EC50 | = | 25000.0 | nM | 4.60 |
| CHEMBL110224 | — | EC50 | = | 26400.0 | nM | 4.58 |
| CHEMBL110175 | — | EC50 | = | 29300.0 | nM | 4.53 |
| CHEMBL106554 | — | EC50 | = | 113000.0 | nM | - |