Assay Detail
Functional
CHEMBL710223
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Compound was evaluated for its ability to Inhibit HIV replication in MT-4 cells
4
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MT4 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Synthesis and anti-HIV activity of 9-[(2R-5R)-2,5-dihydro-5-(phosphonomethoxy)-2-furanyl]-2,6-diaminopurine
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.09 | 5.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL484 | ADEFOVIR | 3.0 | 2 | 5.70 |
| CHEMBL420843 | — | — | 1 | 5.37 |
| CHEMBL105562 | — | — | 1 | 4.08 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL484 | ADEFOVIR | IC50 | = | 2000.0 | nM | 5.70 |
| CHEMBL420843 | — | IC50 | = | 4300.0 | nM | 5.37 |
| CHEMBL484 | ADEFOVIR | IC50 | = | 6500.0 | nM | 5.19 |
| CHEMBL105562 | — | IC50 | = | 82500.0 | nM | 4.08 |