Assay Detail
Functional
CHEMBL710369
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Inhibitory activity against 100I strain and 103N strain of HIV-I in MT-4 cell was determined
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MT4 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Evolution of anti-HIV drug candidates. Part 2: Diaryltriazine (DATA) analogues.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 5.60 | 5.90 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL71728 | — | — | 1 | 5.90 |
| CHEMBL305838 | — | — | 1 | 5.60 |
| CHEMBL306385 | — | — | 1 | 5.50 |
| CHEMBL302551 | — | — | 1 | 5.40 |
| CHEMBL72529 | — | — | 1 | - |
| CHEMBL431572 | — | — | 1 | - |
| CHEMBL73008 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL71728 | — | IC50 | = | 1260.0 | nM | 5.90 |
| CHEMBL305838 | — | IC50 | = | 2510.0 | nM | 5.60 |
| CHEMBL306385 | — | IC50 | = | 3160.0 | nM | 5.50 |
| CHEMBL302551 | — | IC50 | = | 3980.0 | nM | 5.40 |
| CHEMBL72529 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL431572 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL73008 | — | IC50 | > | 10000.0 | nM | - |