Assay Detail
Functional
CHEMBL710377
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Inhibitory activity against 103N strain and 181C strain of HIV-I in MT-4 cell was determined
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MT4 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Evolution of anti-HIV drug candidates. Part 2: Diaryltriazine (DATA) analogues.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 6.88 | 7.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL71728 | — | — | 1 | 7.30 |
| CHEMBL306385 | — | — | 1 | 6.90 |
| CHEMBL305838 | — | — | 1 | 6.90 |
| CHEMBL302551 | — | — | 1 | 6.40 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL71728 | — | IC50 | = | 50.0 | nM | 7.30 |
| CHEMBL306385 | — | IC50 | = | 126.0 | nM | 6.90 |
| CHEMBL305838 | — | IC50 | = | 126.0 | nM | 6.90 |
| CHEMBL302551 | — | IC50 | = | 398.0 | nM | 6.40 |