Assay Detail
Binding
CHEMBL710808
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Inhibition of matrix metalloprotease-9 (MMP-9).
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Protease inhibitors: current status and future prospects.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 7.77 | 9.24 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL440498 | CTS-1027 | 2.0 | 1 | 9.24 |
| CHEMBL514138 | CGS-27023A | — | 1 | 8.10 |
| CHEMBL115653 | CIPEMASTAT | 2.0 | 1 | 7.23 |
| CHEMBL261932 | TANOMASTAT | 2.0 | 1 | 6.52 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL440498 | CTS-1027 | Ki | = | 0.58 | nM | 9.24 |
| CHEMBL514138 | CGS-27023A | Ki | = | 8.0 | nM | 8.10 |
| CHEMBL115653 | CIPEMASTAT | Ki | = | 59.0 | nM | 7.23 |
| CHEMBL261932 | TANOMASTAT | Ki | = | 301.0 | nM | 6.52 |