Assay Detail
Binding
CHEMBL710816
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Inhibition of recombinant human matrix metalloprotease-9
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Synthesis and biological activity of selective azasugar-based TACE inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 7.23 | 7.85 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL43087 | — | — | 1 | 7.85 |
| CHEMBL288664 | — | — | 1 | 7.11 |
| CHEMBL41821 | — | — | 1 | 7.01 |
| CHEMBL288843 | — | — | 1 | 6.93 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL43087 | — | Ki | = | 14.24 | nM | 7.85 |
| CHEMBL288664 | — | Ki | = | 77.75 | nM | 7.11 |
| CHEMBL41821 | — | Ki | = | 98.2 | nM | 7.01 |
| CHEMBL288843 | — | Ki | = | 118.37 | nM | 6.93 |