Assay Detail
Functional
CHEMBL711592
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Tested in vitro for the antiviral activity in MT-4 cells infected with HIV-1
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MT4 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Increase of the anti-HIV activity of D4T in human T-cell culture by the use of the sate pronucleotide approach
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 7.18 | 7.80 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL103260 | — | — | 1 | 7.80 |
| CHEMBL991 | STAVUDINE | 4.0 | 1 | 6.55 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL103260 | — | EC50 | = | 16.0 | nM | 7.80 |
| CHEMBL991 | STAVUDINE | EC50 | = | 280.0 | nM | 6.55 |