Assay Detail
Functional
CHEMBL711675
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Anti-proliferative activity against MDA-435 cells mediated by HDAC inhibition
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MDA-435 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Heterocyclic ketones as inhibitors of histone deacetylase.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 4.97 | 5.64 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL127953 | — | — | 1 | 5.64 |
| CHEMBL125416 | — | — | 1 | 4.30 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL127953 | — | IC50 | = | 2300.0 | nM | 5.64 |
| CHEMBL125416 | — | IC50 | = | 50000.0 | nM | 4.30 |