Assay Detail
Functional
CHEMBL711807
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Effective concentration of compound against HIV-1 IIIB strain in MT-4 cells
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MT4 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
New bicyclam-GalCer analogue conjugates: synthesis and in vitro anti-HIV activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 6 | 6.49 | 8.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL129 | ZIDOVUDINE | 4.0 | 1 | 8.00 |
| CHEMBL18442 | PLERIXAFOR | 4.0 | 1 | 7.19 |
| CHEMBL145521 | — | — | 1 | 6.16 |
| CHEMBL3215409 | — | — | 1 | 5.55 |
| CHEMBL3215411 | — | — | 1 | 5.54 |
| CHEMBL3215412 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL129 | ZIDOVUDINE | EC50 | = | 9.9 | nM | 8.00 |
| CHEMBL18442 | PLERIXAFOR | EC50 | = | 65.0 | nM | 7.19 |
| CHEMBL145521 | — | EC50 | = | 690.0 | nM | 6.16 |
| CHEMBL3215409 | — | EC50 | = | 2800.0 | nM | 5.55 |
| CHEMBL3215411 | — | EC50 | = | 2900.0 | nM | 5.54 |
| CHEMBL3215412 | — | EC50 | > | 100000.0 | nM | - |