Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL712358

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Inhibitory activity against HIV-1 IIIB in MT-4 infected cells
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type MT4
Confidence 1 — Organism
Curated By Intermediate

Target

MT4 (CHEMBL388)
Type CELL-LINE
Organism Homo sapiens

Publication

A new class of anti-HIV agents: synthesis and activity of conjugates of HIV protease inhibitors with a reverse transcriptase inhibitor.
Kimura T, Matsumoto H, Matsuda T, Hamawaki T, Akaji K, Kiso Y.
Bioorg Med Chem Lett (1999) 9 : 803 -806
PubMed 10206539 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 9.24 9.24

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL414640 1 9.24

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL414640 EC50 = 0.57 nM 9.24