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Assay Detail

CHEMBL712599

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibitory activity against muscle Glycogen Phosphorylase a
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Tissue Muscle tissue
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Glycogen phosphorylase, liver form (CHEMBL2568)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Synthesis of and a comparative study on the inhibition of muscle and liver glycogen phosphorylases by epimeric pairs of d-gluco- and d-xylopyranosylidene-spiro-(thio)hydantoins and N-(d-glucopyranosyl) amides.
Somsák L, Kovács L, Tóth M, Osz E, Szilágyi L, Györgydeák Z, Dinya Z, Docsa T, Tóth B, Gergely P.
J Med Chem (2001) 44 : 2843 -2848
PubMed 11495595 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 4.96 4.96

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL489798 1 4.96

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL489798 Ki = 10900.0 nM 4.96