Assay Detail
Binding
CHEMBL712900
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Inhibition of matrix metalloprotease-9
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Discovery and characterization of the potent, selective and orally bioavailable MMP inhibitor ABT-770.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.42 | 6.92 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL40143 | — | — | 1 | 6.92 |
| CHEMBL41943 | — | — | 1 | 5.92 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL40143 | — | IC50 | = | 120.0 | nM | 6.92 |
| CHEMBL41943 | — | IC50 | = | 1200.0 | nM | 5.92 |