Assay Detail
Functional
CHEMBL713550
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Concentration of compound required to reduce MT-4 cell viability by 50%
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MT4 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Chicoric acid analogues as HIV-1 integrase inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 4.26 | 4.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL29660 | CHICORIC ACID | — | 1 | 4.40 |
| CHEMBL282731 | CICHORIC ACID | — | 1 | 4.35 |
| CHEMBL29369 | — | — | 1 | 4.33 |
| CHEMBL30455 | — | — | 1 | 4.22 |
| CHEMBL129 | ZIDOVUDINE | 4.0 | 1 | 4.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL29660 | CHICORIC ACID | IC50 | = | 39700.0 | nM | 4.40 |
| CHEMBL282731 | CICHORIC ACID | IC50 | = | 45000.0 | nM | 4.35 |
| CHEMBL29369 | — | IC50 | = | 47100.0 | nM | 4.33 |
| CHEMBL30455 | — | IC50 | = | 60000.0 | nM | 4.22 |
| CHEMBL129 | ZIDOVUDINE | IC50 | = | 100000.0 | nM | 4.00 |