Assay Detail
Functional
CHEMBL713722
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In vitro inhibition of translation in luciferase SP6 control plasmid
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
New inhibitors of bacterial protein synthesis from a combinatorial library of macrocycles.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 4.94 | 7.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1384 | KANAMYCIN | 4.0 | 1 | 7.10 |
| CHEMBL114170 | — | — | 1 | 4.89 |
| CHEMBL113977 | — | — | 1 | 4.60 |
| CHEMBL325265 | — | — | 1 | 4.46 |
| CHEMBL325902 | — | — | 1 | 4.30 |
| CHEMBL113875 | — | — | 1 | 4.30 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1384 | KANAMYCIN | IC50 | = | 80.0 | nM | 7.10 |
| CHEMBL114170 | — | IC50 | = | 13000.0 | nM | 4.89 |
| CHEMBL113977 | — | IC50 | = | 25000.0 | nM | 4.60 |
| CHEMBL325265 | — | IC50 | = | 35000.0 | nM | 4.46 |
| CHEMBL325902 | — | IC50 | = | 50000.0 | nM | 4.30 |
| CHEMBL113875 | — | IC50 | = | 50000.0 | nM | 4.30 |