Assay Detail
Functional
CHEMBL714464
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Compound was tested for its anti HIV-1 activity in MT-4 cells.
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MT4 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Synthesis of the pyrimidine analog of 4,5,6,7-tetrahydroimidazo[4,5,1-jk][1,4]benzodiazepin-2(1H)one (TIBO) potential for HIV-1 inhibition
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.07 | 7.38 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL293498 | — | — | 1 | 7.38 |
| CHEMBL82396 | — | — | 1 | 6.75 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL293498 | — | IC50 | = | 42.0 | nM | 7.38 |
| CHEMBL82396 | — | IC50 | = | 180.0 | nM | 6.75 |