Assay Detail
Functional
CHEMBL714513
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50% inhibition against mast cell degranulation by measuring the content of beta-glucuronidase in the supernatant
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Rattus norvegicus |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Synthesis and antiinflammatory evaluation of 9-anilinoacridine and 9-phenoxyacridine derivatives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 4.69 | 4.71 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL142346 | — | — | 1 | 4.71 |
| CHEMBL142830 | — | — | 1 | 4.68 |
| CHEMBL140382 | — | — | 1 | 4.68 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL142346 | — | IC50 | = | 19500.0 | nM | 4.71 |
| CHEMBL142830 | — | IC50 | = | 21000.0 | nM | 4.68 |
| CHEMBL140382 | — | IC50 | = | 20700.0 | nM | 4.68 |