Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL714718

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibitory concentration against melatonin receptor by nonlinear fiting strategies
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Coturnix
Confidence 4 — Cell-line / Tissue
Curated By Autocuration

Target

Melatonin receptor (CHEMBL2094268)
Type PROTEIN FAMILY
Organism Homo sapiens

Publication

Conformationally restrained melatonin analogues: synthesis, binding affinity for the melatonin receptor, evaluation of the biological activity, and molecular modeling study.
Spadoni G, Balsamini C, Diamantini G, Di Giacomo B, Tarzia G, Mor M, Plazzi PV, Rivara S, Lucini V, Nonno R, Pannacci M, Fraschini F, Stankov BM.
J Med Chem (1997) 40 : 1990 -2002
PubMed 9207940 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.15 5.15

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL14701 1 5.15

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL14701 IC50 = 7100.0 nM 5.15