Assay Detail
Binding
CHEMBL715230
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Inhibition of Matrix metalloprotease-9
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Expert |
Publication
Heteroaryl and cycloalkyl sulfonamide hydroxamic acid inhibitors of matrix metalloproteinases.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 6.68 | 7.16 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL82487 | — | — | 1 | 7.16 |
| CHEMBL421131 | — | — | 1 | 6.98 |
| CHEMBL81113 | — | — | 1 | 6.74 |
| CHEMBL78826 | — | — | 1 | 6.63 |
| CHEMBL1169492 | — | — | 1 | 6.50 |
| CHEMBL310359 | — | — | 1 | 6.05 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL82487 | — | IC50 | = | 70.0 | nM | 7.16 |
| CHEMBL421131 | — | IC50 | = | 104.0 | nM | 6.98 |
| CHEMBL81113 | — | IC50 | = | 181.0 | nM | 6.74 |
| CHEMBL78826 | — | IC50 | = | 236.0 | nM | 6.63 |
| CHEMBL1169492 | — | IC50 | = | 318.0 | nM | 6.50 |
| CHEMBL310359 | — | IC50 | = | 900.0 | nM | 6.05 |