Assay Detail
Binding
CHEMBL715424
Review assay metadata, readout intent, target linkage, and publication context from the same page.
pA2 value for human melanocortin receptor Melanocortin-3 receptor
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Structure-activity studies of the melanocortin peptides: discovery of potent and selective affinity antagonists for the hMC3 and hMC4 receptors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 2 | 8.15 | 8.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2096742 | — | — | 1 | 8.70 |
| CHEMBL1161320 | — | — | 1 | 7.60 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2096742 | — | Kd | = | 1.995 | nM | 8.70 |
| CHEMBL1161320 | — | Kd | = | 25.12 | nM | 7.60 |