Assay Detail
Binding
CHEMBL715723
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Concentration for half maximal activation of metabotropic glutamate mGluR5a in human
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Metabotropic glutamate receptors: novel targets for drug development.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 6.11 | 6.82 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL279956 | QUISQUALATE | — | 1 | 6.82 |
| CHEMBL575060 | GLUTAMIC ACID | 3.0 | 1 | 5.39 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL279956 | QUISQUALATE | EC50 | = | 150.0 | nM | 6.82 |
| CHEMBL575060 | GLUTAMIC ACID | EC50 | = | 4100.0 | nM | 5.39 |