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Assay Detail

CHEMBL715953

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding Affinity (pKi) towards Melatonin receptor type 1A
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Melatonin receptor type 1A (CHEMBL1945)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Three-dimensional quantitative structure-activity relationship studies on selected MT1 and MT2 melatonin receptor ligands: requirements for subtype selectivity and intrinsic activity modulation.
Rivara S, Mor M, Silva C, Zuliani V, Vacondio F, Spadoni G, Bedini A, Tarzia G, Lucini V, Pannacci M, Fraschini F, Plazzi PV.
J Med Chem (2003) 46 : 1429 -1439
PubMed 12672242 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 6.85 6.85

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL34327 1 6.85

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL34327 Ki = 141.25 nM 6.85