Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL718191

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibitory activity against human Melanocortin 3 receptor was determined
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Melanocortin receptor 3 (CHEMBL4644)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Structure-activity relationships of novel cyclic alpha-MSH/beta-MSH hybrid analogues that lead to potent and selective ligands for the human MC3R and human MC5R.
Balse-Srinivasan P, Grieco P, Cai M, Trivedi D, Hruby VJ.
J Med Chem (2003) 46 : 3728 -3733
PubMed 12904077 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 7.27 7.27

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL415333 1 7.27

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL415333 Ki = 54.0 nM 7.27