Assay Detail
Binding
CHEMBL718669
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Inhibition of human Matrix metalloprotease-1
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Expert |
Publication
Asymmetric synthesis of BB-3497--a potent peptide deformylase inhibitor.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.83 | 5.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL308333 | ACTINONIN | — | 1 | 5.96 |
| CHEMBL431210 | — | — | 1 | 5.70 |
| CHEMBL84969 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL308333 | ACTINONIN | IC50 | = | 1100.0 | nM | 5.96 |
| CHEMBL431210 | — | IC50 | = | 2000.0 | nM | 5.70 |
| CHEMBL84969 | — | IC50 | > | 100000.0 | nM | - |