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Assay Detail

CHEMBL729336

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
The compound is evaluated for the inhibitory activity against HIV-1 ADA, monocyte-tropic in Mono/Mac cells.
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Confidence 1 — Organism
Curated By Intermediate

Target

Homo sapiens (CHEMBL372)
Type ORGANISM
Organism Homo sapiens

Publication

New alkenyldiarylmethanes with enhanced potencies as anti-HIV agents which act as non-nucleoside reverse transcriptase inhibitors.
Cushman M, Casimiro-Garcia A, Hejchman E, Ruell JA, Huang M, Schaeffer CA, Williamson K, Rice WG, Buckheit RW.
J Med Chem (1998) 41 : 2076 -2089
PubMed 9622549 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 6.55 6.55

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL294840 1 6.55

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL294840 EC50 = 280.0 nM 6.55