Assay Detail
Binding
CHEMBL729456
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Compound was evaluated for the Inhibition of Monoamine oxidase B
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
Amine oxidase [flavin-containing] B (CHEMBL2993) ↗| Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
Publication
Selective and potent monoamine oxidase type B inhibitors: 2-substituted 5-aryltetrazole derivatives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 8.34 | 8.34 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL17092 | — | — | 1 | 8.34 |
| CHEMBL16781 | — | — | 1 | 8.34 |
| CHEMBL17079 | — | — | 1 | 8.34 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL17092 | — | IC50 | = | 4.6 | nM | 8.34 |
| CHEMBL16781 | — | IC50 | = | 4.6 | nM | 8.34 |
| CHEMBL17079 | — | IC50 | = | 4.6 | nM | 8.34 |