Amine oxidase [flavin-containing] B · SINGLE PROTEIN · Rattus norvegicus
This target will appear in recent viewed items on this browser. Use the demo workspace to preview watch rules and decision queues.
Move to another high-traffic target or paste a specific ChEMBL target ID.
Structured disease, protein, and project context should read before the lower-level identity rail.
As of 2026-09-13Protein identity stays anchored to UniProt P19643. Use UniProt P19643 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P19643 as the stable identity anchor, then attach disease evidence before program review.
Amine oxidase [flavin-containing] B
Review this target as Amine oxidase [flavin-containing] B, mapped to UniProt P19643. Sequence length is 520 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Amine oxidase [flavin-containing] B as ChEMBL target CHEMBL2993, mapped to UniProt P19643. Disease framing currently uses the Open Targets-ready proxy contract.
Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.
Choose the first block or source based on the question you are trying to answer.
Start here when your first question is whether Amine oxidase [flavin-containing] B is the right protein anchor across sources, using UniProt P19643 as the stable mapping.
Jump to Protein ContextUse this block first when you need the strongest disease program and evidence level in one place.
Jump to Disease ContextOpen the one-page evidence card when you want the rationale, activity base, and attribution together.
Open Review-ready CardVerify identity, organism, and the fastest next research jumps from the same page.
| Preferred Name | Amine oxidase [flavin-containing] B |
| Target Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
| UniProt | P19643 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Amine oxidase [flavin-containing] B |
| UniProt Accession | P19643 |
| Component Type | Protein |
| Sequence Length | 520 aa |
Amine oxidase [flavin-containing] B
Review this target as Amine oxidase [flavin-containing] B, mapped to UniProt P19643. Sequence length is 520 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL2022927 | 10.6 | IC50 | 0.025 | Preclinical |
| CHEMBL276076 | 9.4 | IC50 | 0.4 | Preclinical |
| CHEMBL1760721 | 9.35 | Ki | 0.45 | Preclinical |
| CHEMBL8706 | 9.3 | IC50 | 0.5 | Clinical |
| CHEMBL274029 | 9.3 | IC50 | 0.5 | Preclinical |
| CHEMBL274030 | 9.22 | IC50 | 0.6 | Preclinical |
| CHEMBL1760722 | 9.22 | Ki | 0.6 | Preclinical |
| CHEMBL45069 | 9.12 | Ki | 0.75 | Preclinical |
| CHEMBL274513 | 9.1 | IC50 | 0.8 | Preclinical |
| CHEMBL19004 | 9.05 | IC50 | 0.9 | Clinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 109 | 364 | 6.4 |
| tissue-based format | 91 | 315 | 6.0 |
| single protein format | 69 | 302 | 6.5 |
| mitochondrion format | 33 | 190 | 5.8 |
| organism-based format | 22 | 0 | — |
| cell-based format | 3 | 37 | 6.9 |
| cell membrane format | 2 | 14 | 6.4 |
| cell-free format | 1 | 1 | 8.5 |
| subcellular format | 1 | 1 | 7.3 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| organism-based format | 7 | 0 | — |
| assay format | 5 | 1 | 4.7 |
| tissue-based format | 1 | 1 | 4.0 |