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Assay Detail

CHEMBL729490

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Competitive inhibition of Bovine liver Monoamine Oxidase B at 30 degree C (pH= 9.0)
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Bos taurus
Tissue Liver
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Amine oxidase [flavin-containing] B (CHEMBL2993)
Type SINGLE PROTEIN
Organism Rattus norvegicus

Publication

Stereoisomers of allenic amines as inactivators of monoamine oxidase type B. Stereochemical probes of the active site.
Smith RA, White RL, Krantz A.
J Med Chem (1988) 31 : 1558 -1566
PubMed 3397993 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 4.00 4.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL19969 1 4.00

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL19969 Ki = 100000.0 nM 4.00