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Assay Detail

CHEMBL730884

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Binding
Inhibitory activity against Monoamine oxidase at the selectivity factor of 4000
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Amine oxidase [flavin-containing] A (CHEMBL3681)
Type SINGLE PROTEIN
Organism Mus musculus

Publication

Inhibition of amine oxidases activity by 1-acetyl-3,5-diphenyl-4,5-dihydro-(1H)-pyrazole derivatives.
Manna F, Chimenti F, Bolasco A, Secci D, Bizzarri B, Befani O, Turini P, Mondovi B, Alcaro S, Tafi A.
Bioorg Med Chem Lett (2002) 12 : 3629 -3633
PubMed 12443791 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.40 7.40

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL121432 1 7.40

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL121432 IC50 = 40.0 nM 7.40