Assay Detail
Functional
CHEMBL731341
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Tested for electrically induced smooth muscle contractions from mouse vas deferens expressed in delta opioid receptors
5
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
De novo design, synthesis, and biological activities of high-affinity and selective non-peptide agonists of the delta-opioid receptor.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 5 | 7.14 | 8.74 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL150625 | — | — | 1 | 8.74 |
| CHEMBL143592 | — | — | 3 | 7.07 |
| CHEMBL356587 | — | — | 1 | 6.76 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL150625 | — | EC50 | = | 1.8 | nM | 8.74 |
| CHEMBL143592 | — | EC50 | = | 85.0 | nM | 7.07 |
| CHEMBL356587 | — | EC50 | = | 174.0 | nM | 6.76 |
| CHEMBL143592 | — | EC50 | = | 210.0 | nM | 6.68 |
| CHEMBL143592 | — | EC50 | = | 360.0 | nM | 6.44 |