Assay Detail
Binding
CHEMBL732096
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Inhibition of Mitogen-activated protein kinase p38
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 4 — Cell-line / Tissue |
| Curated By | Autocuration |
Publication
From imidazoles to pyrimidines: new inhibitors of cytokine release.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.26 | 6.44 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL10 | SB-203580 | — | 1 | 6.44 |
| CHEMBL111456 | — | — | 1 | 5.40 |
| CHEMBL441811 | — | — | 1 | 5.29 |
| CHEMBL93079 | — | — | 1 | 4.72 |
| CHEMBL92723 | — | — | 1 | 4.44 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL10 | SB-203580 | IC50 | = | 360.0 | nM | 6.44 |
| CHEMBL111456 | — | IC50 | = | 4000.0 | nM | 5.40 |
| CHEMBL441811 | — | IC50 | = | 5100.0 | nM | 5.29 |
| CHEMBL93079 | — | IC50 | = | 19000.0 | nM | 4.72 |
| CHEMBL92723 | — | IC50 | = | 36000.0 | nM | 4.44 |