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Assay Detail

CHEMBL732635

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of Mitogen-activated protein kinase p38
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 4 — Cell-line / Tissue
Curated By Autocuration

Target

MAP kinase p38 (CHEMBL2094115)
Type PROTEIN FAMILY
Organism Homo sapiens

Publication

Kinase inhibitors: not just for kinases anymore.
McGovern SL, Shoichet BK.
J Med Chem (2003) 46 : 1478 -1483
PubMed 12672248 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 6.30 7.30

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL10 SB-203580 1 7.30
CHEMBL36450 1 5.30

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL10 SB-203580 IC50 = 50.0 nM 7.30
CHEMBL36450 IC50 = 5000.0 nM 5.30