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Assay Detail

CHEMBL732889

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of p38 kinase
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 4 — Cell-line / Tissue
Curated By Autocuration

Target

MAP kinase p38 (CHEMBL2094115)
Type PROTEIN FAMILY
Organism Homo sapiens

Publication

BREED: Generating novel inhibitors through hybridization of known ligands. Application to CDK2, p38, and HIV protease.
Pierce AC, Rao G, Bemis GW.
J Med Chem (2004) 47 : 2768 -2775
PubMed 15139755 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.62 7.62

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL96741 1 7.62

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL96741 IC50 = 24.0 nM 7.62