Assay Detail
Binding
CHEMBL732890
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Inhibition of Mitogen-activated protein kinase p38
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 4 — Cell-line / Tissue |
| Curated By | Autocuration |
Publication
Identification of novel inhibitors of the transforming growth factor beta1 (TGF-beta1) type 1 receptor (ALK5).
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 4.91 | 5.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL266707 | — | — | 1 | 5.00 |
| CHEMBL269341 | — | — | 1 | 4.82 |
| CHEMBL266706 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL266707 | — | IC50 | = | 10000.0 | nM | 5.00 |
| CHEMBL269341 | — | IC50 | = | 15000.0 | nM | 4.82 |
| CHEMBL266706 | — | IC50 | > | 50000.0 | nM | - |