Assay Detail
Functional
CHEMBL733564
Review assay metadata, readout intent, target linkage, and publication context from the same page.
In vitro inhibitory activity against electrically evoked contractions of in mouse vas deferens (MVD)
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Tissue | Vas deferens |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Potent delta-opioid receptor agonists containing the Dmt-Tic pharmacophore.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 9.95 | 10.82 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL607401 | — | — | 1 | 10.82 |
| CHEMBL607479 | — | — | 1 | 10.59 |
| CHEMBL606603 | — | — | 1 | 10.59 |
| CHEMBL109390 | — | — | 1 | 10.46 |
| CHEMBL442577 | — | — | 1 | 9.92 |
| CHEMBL26861 | — | — | 1 | 9.52 |
| CHEMBL278789 | DERMORPHIN | — | 1 | 7.78 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL607401 | — | IC50 | = | 0.015 | nM | 10.82 |
| CHEMBL607479 | — | IC50 | = | 0.026 | nM | 10.59 |
| CHEMBL606603 | — | IC50 | = | 0.026 | nM | 10.59 |
| CHEMBL109390 | — | IC50 | = | 0.035 | nM | 10.46 |
| CHEMBL442577 | — | IC50 | = | 0.12 | nM | 9.92 |
| CHEMBL26861 | — | IC50 | = | 0.3 | nM | 9.52 |
| CHEMBL278789 | DERMORPHIN | IC50 | = | 16.5 | nM | 7.78 |