Assay Detail
Binding
CHEMBL735049
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Inhibition of Mitogen-activated protein kinase p38 alpha
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Expert |
Publication
Pyrroles and other heterocycles as inhibitors of p38 kinase.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.92 | 8.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL88486 | — | — | 1 | 8.30 |
| CHEMBL316275 | — | — | 1 | 8.05 |
| CHEMBL10 | SB-203580 | — | 1 | 7.41 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL88486 | — | IC50 | = | 5.0 | nM | 8.30 |
| CHEMBL316275 | — | IC50 | = | 9.0 | nM | 8.05 |
| CHEMBL10 | SB-203580 | IC50 | = | 39.0 | nM | 7.41 |