Assay Detail
Binding
CHEMBL743980
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of [3H]QNB binding towards muscarinic acetylcholine receptor in guinea pig ileum.
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Cavia porcellus |
| Tissue | Ileum |
| Confidence | 4 — Cell-line / Tissue |
| Curated By | Autocuration |
Target
Muscarinic acetylcholine receptors; M1 & M2 (CHEMBL2095219) ↗| Type | SELECTIVITY GROUP |
| Organism | Homo sapiens |
Publication
Crystal, solution, and molecular modeling structural properties and muscarinic antagonist activity of azaprophen.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 1 | 9.55 | 9.55 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL287868 | AZAPROPHEN | — | 1 | 9.55 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL287868 | AZAPROPHEN | Ki | = | 0.279 | nM | 9.55 |