Assay Detail
Binding
CHEMBL744176
Review assay metadata, readout intent, target linkage, and publication context from the same page.
The compound was tested for binding affinity nisoxatine ligand
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Structure-activity relationships at the monoamine transporters and sigma receptors for a novel series of 9-[3-(cis-3, 5-dimethyl-1-piperazinyl)propyl]carbazole (rimcazole) analogues.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 5.47 | 5.90 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL281594 | VANOXERINE | 3.0 | 1 | 5.90 |
| CHEMBL370805 | COCAINE | 4.0 | 1 | 5.48 |
| CHEMBL2112790 | — | — | 1 | 5.44 |
| CHEMBL314726 | — | — | 1 | 5.07 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL281594 | VANOXERINE | Ki | = | 1270.0 | nM | 5.90 |
| CHEMBL370805 | COCAINE | Ki | = | 3300.0 | nM | 5.48 |
| CHEMBL2112790 | — | Ki | = | 3660.0 | nM | 5.44 |
| CHEMBL314726 | — | Ki | = | 8540.0 | nM | 5.07 |