Norepinephrine transporter · SINGLE PROTEIN · Rattus norvegicus
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As of 2026-09-14Protein identity stays anchored to UniProt Q9WTR4. Use UniProt Q9WTR4 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q9WTR4 as the stable identity anchor, then attach disease evidence before program review.
Transporter
Review this target as Norepinephrine transporter, mapped to UniProt Q9WTR4. ChEMBL maps the protein component as Transporter. Sequence length is 597 aa.
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This review treats Norepinephrine transporter as ChEMBL target CHEMBL304, mapped to UniProt Q9WTR4. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Norepinephrine transporter |
| Target Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
| UniProt | Q9WTR4 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Transporter |
| UniProt Accession | Q9WTR4 |
| Component Type | Protein |
| Sequence Length | 597 aa |
Transporter
Review this target as Norepinephrine transporter, mapped to UniProt Q9WTR4. ChEMBL maps the protein component as Transporter. Sequence length is 597 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL544500 | 9.92 | IC50 | 0.12 | Preclinical |
| CHEMBL1743782 | 9.8 | Ki | 0.16 | Preclinical |
| CHEMBL540617 | 9.8 | Ki | 0.16 | Preclinical |
| CHEMBL1743810 | 9.7 | Ki | 0.2 | Preclinical |
| CHEMBL2093944 | 9.7 | Ki | 0.2 | Preclinical |
| CHEMBL544266 | 9.59 | IC50 | 0.26 | Preclinical |
| CHEMBL2096748 | 9.52 | IC50 | 0.3 | Preclinical |
| CHEMBL545671 | 9.52 | IC50 | 0.3 | Preclinical |
| CHEMBL545201 | 9.49 | IC50 | 0.32 | Preclinical |
| CHEMBL35184 | 9.43 | Ki | 0.37 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 54 | 295 | 6.5 |
| tissue-based format | 42 | 371 | 6.3 |
| assay format | 33 | 190 | 6.7 |
| subcellular format | 20 | 248 | 7.0 |
| cell membrane format | 10 | 63 | 6.8 |
| organism-based format | 2 | 0 | — |
| cell-based format | 1 | 1 | 8.2 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 11 | 144 | 7.1 |
| subcellular format | 6 | 62 | 7.2 |
| tissue-based format | 4 | 111 | 5.9 |
| organism-based format | 1 | 0 | — |