Assay Detail
Functional
CHEMBL744867
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Tested for the binding affinity to human NK2 receptor expressed in Sf-9 insect larval cells using 0.1 nM 2-[125 I] iodohistidyl neurokinin A
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Two novel amino acid derivatives containing side-chain thioamides for the synthesis of photoactivatable peptides
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.83 | 8.11 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL264972 | — | — | 1 | 8.11 |
| CHEMBL217406 | NEUROKININ A | — | 1 | 8.11 |
| CHEMBL412740 | — | — | 1 | 7.27 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL264972 | — | IC50 | = | 7.72 | nM | 8.11 |
| CHEMBL217406 | NEUROKININ A | IC50 | = | 7.7 | nM | 8.11 |
| CHEMBL412740 | — | IC50 | = | 53.36 | nM | 7.27 |