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Assay Detail

CHEMBL745072

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Compound was tested for binding affinity against Muscarinic acetylcholine receptor M4 in NG 108-15 cell homogenates
2
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Cell Type NG 108-15
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Muscarinic acetylcholine receptor M4 (CHEMBL1821)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Design, synthesis and biological activity of some 4-DAMP- related compounds
Tumiatti V, Santi S, Recanatini M, Minarini A, Melchiorre C, Chiarini A, Budriesi R
Bioorg Med Chem Lett (1995) 5 : 2325 -2330
· DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 2 8.35 8.36

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL292857 2 8.36

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL292857 Ki = 4.365 nM 8.36
CHEMBL292857 Ki = 4.677 nM 8.33