Assay Detail
Functional
CHEMBL746248
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In vitro inhibition of PGE-2 production in murine resident peritoneal macrophage
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Analogs of the marine natural product scalaradial lacking the ,-unsaturated aldehyde: effects on human synovial fluid phospholipase A2 and macrophage lipid mediator production
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.87 | 7.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL487005 | SCALARADIAL | — | 1 | 7.40 |
| CHEMBL291715 | — | — | 1 | 6.70 |
| CHEMBL56332 | — | — | 1 | 6.52 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL487005 | SCALARADIAL | IC50 | = | 40.0 | nM | 7.40 |
| CHEMBL291715 | — | IC50 | = | 200.0 | nM | 6.70 |
| CHEMBL56332 | — | IC50 | = | 300.0 | nM | 6.52 |