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Assay Detail

CHEMBL746683

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Activation of murine PPAR alpha ligand binding domain
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Mus musculus
Confidence 9 — Direct single protein target
Curated By Expert

Target

Peroxisome proliferator-activated receptor alpha (CHEMBL2128)
Type SINGLE PROTEIN
Organism Mus musculus

Publication

Identification of a subtype selective human PPARalpha agonist through parallel-array synthesis.
Brown PJ, Stuart LW, Hurley KP, Lewis MC, Winegar DA, Wilson JG, Wilkison WO, Ittoop OR, Willson TM.
Bioorg Med Chem Lett (2001) 11 : 1225 -1227
PubMed 11354382 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 9.00 9.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL21241 GW7647 1 9.00

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL21241 GW7647 EC50 = 1.0 nM 9.00